Diablo Analytical, Inc. has extensive experience in analytical method development for both Gas Chromatography and GC-MS across a broad range of industry applications.
Custom GC and MS Methods
GC Column Selection
GC column selection is critical for successful applications. The right column can result in a robust method, while the wrong column can produce variable or sample-dependant results. Column choice must also be matched to sample and analyte type, injection conditions, detector requirements and system GC resolution. Method development requires an experienced person to choose the best column for an application.
Inlet Selection and External Sampling Devices
Split and splitless injection is used for most GC applications. However, other inlets can provide critical advantages for samples that can not be analyzed with a split inlet. Modern on-column injectors and PTV inlets are reliable and automated. Other inlets are also used for special applications: APEX, thermal desorption, pyrolysis, headspace, purge and trap, etc. Diablo can help determine the best inlet configuration to use for your application.
Many detectors are available for Gas Chromatography. In choosing the best detector to use for a particular application, one must consider the obvious attributes like detection limits, linearity, and selectivity. However, less-obvious characteristics like robustness and ease of use may be equally important.